I recently downloaded the new Update 3 box for Dynamics for Operations which was on windows 2016. I installed Chrome and got this strange error.
ERR_SPDY_INADEQUATE_TRANSPORT_SECURITY
After some searching and trial and error. Here is my workaround/solution.
I used IISCrypto to disable SSL 2.0. Make sure to reboot afterwards.
These are a couple of links that helped me.
http://www.tecfused.com/2016/10/err_spdy_inadequate_transport_security-server-2016/
Don’t ask me why or what. This is a rough fix that worked for me. I am not sure if I broke anything else. I just wanted to use some chrome tools.